Hot off the press news about knee arthritisfrom Maidâ€¦ not all knee pain comes from the knee Neuropathic pain features commonknee OA Lucy Piper writingMedwire News reportedenough patients with knee osteoarthritis (OA) experience pain with neuropathic characteristicsto warrant attempts to diagnose and classify these features, say researchers.They found that among 2176 patients with OA, a third scored positively for neuropathicpain on the Douler Neuropathique (DN4) questionnaire, after patients with reasons other than OAfor such pain had been excluded.
Analysis showed that three of these potentialconfounders â€“ conditions other than OA that cause changescutaneous sensory perceptionson the knee, or cause abnormal sensations over the area of the knee, and referred backor hip pain â€“ were highly specific for neuropathic pain, but less sensitive than the DN4.â€œWhen these factors are absent, the presence of neuropathic pain is unlikely, yet the DN4can sense additional neuropathic featuressome patients,â€� explain the researchers,led by Ã�ngel OteoÃ�lvaro ( General Universitario Gregorio MaraÃ±Ã³n, Maid,Spain). Further confirmation and classifiion ofthese additional features could reveal links
between neuropathophysiology and signs andsymptoms of the condition, they note. Comment: Neuropathic pain may require differenttreatment than pain coming from other sources.