Peripheral neuropathy, this is an often devastatingconditionwhich people develop pain and numbnesstheir hands and feet. Basicallythey're told on the evening news that they should be taking this or that mediion sothat they can get through life. That's treating the smoke and ignoring thefire. Those medicines that you're seeing advertised don't treat the neuropathy, they only treatthe symptoms. But what's causing peripheral neuropathy? Well we know thatAmerica,one of the biggest causes of peripheral neuropathy is being diabetic, which is clearly relatedto the foods that you eat by and large. Becoming a type 2 diabetic amatically increases yourrisk for having peripheral neuropathy and
fact being devastated by it. This is adisease that effects 115 Americans. Let's take a look. So again this is 115 Americansâ€”thisis 20 million Americans afflicted by this disease, that aside from diabetes, we're toldthe cause is unknown. Well maybe that's not exactly true. Last month,the journal Neurology,an incredible study was published describing a relationship between what are called fluoroquinolones,and the risk of developing a peripheral neuropathy. You may not know what fluoroquinolones are,but chances are you may have actually been exposed to fluoroquinolone. These are antibioticsused for treating things like upper respiratory
infections and even urinary tract infections.Things like Levaquin and Cipro are commonly usedwalks. If you have a urinarytract infection, you may have received these mediations. Well, here's what the study showedus: So this is a study publishedSeptember2014 that looked at men between age 45 to 80 years of age followed for a 10 year periodandthis group there were over 6,000 cases of peripheral neuropathy. And they comparedthese individuals to about 25,000 aged match controls, and what they found was that riskfor developing this devastating condition called peripheral neuropathy was doubled inthose individuals exposed to this class of
antibiotics called fluoroquinolones. And whatthe researchers also told us is that, and I quote, quot;Fluoroquinolones have been shownto neurotoxic. Oral fluoroquinolones have also been associated with reported cases ofpsychosis and seizures, which similar to peripheral neuropathy have been shown to be acute eventsoccurring within days of fluoroquinolone use. In light of strong evidence of unnecessaryprescribing of oral fluoroquinolonesthe United States, ians must weigh the riskof PN against the benefits of prescribing FQ when prescribing these ugs to their patients.quot; We've got to practice medicine under the dictumof quot;above all do no harm.quot; One of our most
well respected peer journals is nowtelling us that the use of these mediionsâ€”these fluoroquinolone antibiotics is associatedwith doubling of the risk of peripheral neuropathy. A disease which often is not treatable. Sokeep thatmind the next time you think you need an antibiotic for this or that problem,discuss this study with your treating physician. I'm David Perlmutter.
Hot off the press news about knee arthritisfrom Maidâ€¦ not all knee pain comes from the knee Neuropathic pain features commonknee OA Lucy Piper writingMedwire News reportedenough patients with knee osteoarthritis (OA) experience pain with neuropathic characteristicsto warrant attempts to diagnose and classify these features, say researchers.They found that among 2176 patients with OA, a third scored positively for neuropathicpain on the Douler Neuropathique (DN4) questionnaire, after patients with reasons other than OAfor such pain had been excluded.
Analysis showed that three of these potentialconfounders â€“ conditions other than OA that cause changescutaneous sensory perceptionson the knee, or cause abnormal sensations over the area of the knee, and referred backor hip pain â€“ were highly specific for neuropathic pain, but less sensitive than the DN4.â€œWhen these factors are absent, the presence of neuropathic pain is unlikely, yet the DN4can sense additional neuropathic featuressome patients,â€� explain the researchers,led by Ã�ngel OteoÃ�lvaro ( General Universitario Gregorio MaraÃ±Ã³n, Maid,Spain). Further confirmation and classifiion ofthese additional features could reveal links
between neuropathophysiology and signs andsymptoms of the condition, they note. Comment: Neuropathic pain may require differenttreatment than pain coming from other sources.