Fluoroquinolones and Peripheral Neuropathy
Peripheral neuropathy, this is an often devastatingconditionwhich people develop pain and numbnesstheir hands and feet. Basicallythey're told on the evening news that they should be taking this or that mediion sothat they can get through life. That's treating the smoke and ignoring thefire. Those medicines that you're seeing advertised don't treat the neuropathy, they only treatthe symptoms. But what's causing peripheral neuropathy? Well we know thatAmerica,one of the biggest causes of peripheral neuropathy is being diabetic, which is clearly relatedto the foods that you eat by and large. Becoming a type 2 diabetic amatically increases yourrisk for having peripheral neuropathy and
fact being devastated by it. This is adisease that effects 115 Americans. Let's take a look. So again this is 115 Americansâ€”thisis 20 million Americans afflicted by this disease, that aside from diabetes, we're toldthe cause is unknown. Well maybe that's not exactly true. Last month,the journal Neurology,an incredible study was published describing a relationship between what are called fluoroquinolones,and the risk of developing a peripheral neuropathy. You may not know what fluoroquinolones are,but chances are you may have actually been exposed to fluoroquinolone. These are antibioticsused for treating things like upper respiratory
infections and even urinary tract infections.Things like Levaquin and Cipro are commonly usedwalks. If you have a urinarytract infection, you may have received these mediations. Well, here's what the study showedus: So this is a study publishedSeptember2014 that looked at men between age 45 to 80 years of age followed for a 10 year periodandthis group there were over 6,000 cases of peripheral neuropathy. And they comparedthese individuals to about 25,000 aged match controls, and what they found was that riskfor developing this devastating condition called peripheral neuropathy was doubled inthose individuals exposed to this class of
antibiotics called fluoroquinolones. And whatthe researchers also told us is that, and I quote, quot;Fluoroquinolones have been shownto neurotoxic. Oral fluoroquinolones have also been associated with reported cases ofpsychosis and seizures, which similar to peripheral neuropathy have been shown to be acute eventsoccurring within days of fluoroquinolone use. In light of strong evidence of unnecessaryprescribing of oral fluoroquinolonesthe United States, ians must weigh the riskof PN against the benefits of prescribing FQ when prescribing these ugs to their patients.quot; We've got to practice medicine under the dictumof quot;above all do no harm.quot; One of our most
well respected peer journals is nowtelling us that the use of these mediionsâ€”these fluoroquinolone antibiotics is associatedwith doubling of the risk of peripheral neuropathy. A disease which often is not treatable. Sokeep thatmind the next time you think you need an antibiotic for this or that problem,discuss this study with your treating physician. I'm David Perlmutter.
How Dietary Supplements Can Help with Neuropathy
Hi, this is Silvester and I'm goingto talk to you about justgeneral why we use supplementspatients with neuropathy.We really have worked hard at trying to establish a neuropathy relief center at our .What we're after is to try to give the patient, besides just the normal pharmaceutical treatmentthat you can get at most of the s around that just give you a pill to take and it makesyou feel a little better, but really doesn't solve the problem we try to give you solutionsto get your neuropathy better, to improve them. We've invested a lottrying tolearn about supplements and the role that they play, using pharmaceuticals appropriatelyto give you relief, using electrical nerve
signal therapy with local anesthetic blockto try and regenerate nerves, laser therapy has been very effective at helping nervesget better not just feel better, but also get better. Also, there's surgery,theright person. Sometimes nerves are pinchedassociationwith having neuropathy the nerves can be entrapped, just like carpal tunnel synome can causepain under you hand, the same thing can happenyour foot and lower extremity, so by decompressingthose nerves, you can have significant relief and amatically improve nerve function, andin the case of patients with diabetes, much lower risk of future diabetic foot ulcers,and that's been demonstrated by a lot of
studies that have been done.How supplements work basically is, a lot of them are geared towards helping the cell,the nerve cell, have enough energy. The nerve cellsgeneral are very high energy consumers,and they're very small, very long, skinny nerves and if they don't have enough energy,they can't heal themselves and repair themselves or maintain this electrogradient that'sacross the nerve. For example, how a nerve carries an impulseis there's an electrical current and there's a little gate that opens and lets calciumin and out of the cell, and it creates an electrical current across this nerve. To establishthat, the cell has to pump that calcium out
to keep that gradient there. It has to workall of the time, and what happens when you get not enough energy, those gates just stayopen, the nerve doesn't function and you start getting feelings like burning, tingling,electrical sensation, and eventually numbness because the nerve doesn't work. I've actuallyhad patients who I've operated on without local anesthetic and they haven't felt ita bit because they're so profoundly neuropathic their nerves are so far damaged that theydon't feel anything. That's a major cause of falls, it's amajor cause of ulcers, it's a major cause of calluses I've had patients break theirfeet and not feel it they comeand they
have a swollen, red foot and they don'tknow why, and you take xrays and they have all of these fractures inside of their foot.There are ways, if you ch it early enough, and use the right supplements and keep yourblood sugar down, that you can preserve your nerve function until latelife and havea healthy life. Thanks for listening.
How Acetyl L Carnitine Helps Treat Neuropathy
Hi this is Silvester and I'm going totalk to you a little bit today about one of the supplements we use for our patients withdiabetic neuropathy that seems to have a big effecthelping them and their nerves getbetter. There was actually a study done with this supplement where they took 1,275 patientswho took this supplement, and they actually showed an increasenerve fiber density,after taking this supplement for 52 weeks. They also showed that they had significantdecreasetheir pain, and they had significantly improved quality of life after taking thissupplement. It's acetyl l carnitine. Acetyl l carnitine worksthe same way as manyother antioxidants and many other nerve healing
supplements. They help the nerve make moreenergy so it can heal itself and regrow. If you want to start your nerves on the pathof healing, not just treating them with prescription mediion, which really all they do is helpthe nerve feel better while it's dying, you can actually heal them with acetyl l carnitineand good studies have backed that up. With all supplements you want to check with your to make sure it's okay to start taking them but acetyl l carnitine can have a bigbenefit for patients with neuropathy.