Peripheral Neurological Disorders Caused

Peripheral Neuropathy Tingling Numb FeetLegs Symptoms Resolved DavisClinc

When you initially presented to the office,you presented with numbness, tingling, and irritationthe lower extremities and feet.We've managed this condition with our peripheral neuropathy program. How have you done withthe management and how are you doing today? Oh I'm feeling fine, I'm feeling great. WhenI camehere I thought I'd have to live with pain the rest of my life and it's great,really great. Well we're very very proud to have you here as a patient and congratulationson your results. Thank you , thank you a lot.

Peripheral Nervous System Disorders Diagnosis and Treatment

The peripheral nervous system is the partof the nervous system that excludes or is outside of the brain and the spinal cord.We take care of patients that have disorders that affect the motor neurons, which livein the spinal cord – the peripheral nerves that extend out into the arms and legs aswell as the muscles and the connection between the nerves and the muscles. Some of the disordersthat a nerve and muscle a disease will evaluate and develop care plans for includemuscle disorders such as muscular dystrophy, polymyositis, dermatomyositis, peripheralneuropathies such as Charcot Marie Tooth disease or hereditary neuropathy and as well as theneuromuscular junction disorders such as myasthenia

gravis. Some symptoms that can be associatedwith the peripheral nervous system include generalized weakness, fatigue, numbness, tingling,sometimes pain can be caused by disorders of the peripheral nerve. The evaluation ofa patient with a possible peripheral nervous system disorder first begins with the verycareful history to understand how the symptoms started and how they affect the patient. Fromthe history we extend to the physical exam, which helps us determine what sort of deficitsmay be impacting the patient's function. From there we design a targeted testing strategyto to try to pinpoint exactly what's causing the symptoms. It's a very exciting time inneuromuscular medicine because the more we

understand about how these diseases occur,the more that we can develop very targeted, personalized treatments to help either stopor reverse the disease. In many cases there may not be a specific cure but we can reducethe symptoms through a comprehensive treatment plan.

Fluoroquinolones and Peripheral Neuropathy

Peripheral neuropathy, this is an often devastatingconditionwhich people develop pain and numbnesstheir hands and feet. Basicallythey're told on the evening news that they should be taking this or that mediion sothat they can get through life. That's treating the smoke and ignoring thefire. Those medicines that you're seeing advertised don't treat the neuropathy, they only treatthe symptoms. But what's causing peripheral neuropathy? Well we know thatAmerica,one of the biggest causes of peripheral neuropathy is being diabetic, which is clearly relatedto the foods that you eat by and large. Becoming a type 2 diabetic amatically increases yourrisk for having peripheral neuropathy and

fact being devastated by it. This is adisease that effects 115 Americans. Let's take a look. So again this is 115 Americans—thisis 20 million Americans afflicted by this disease, that aside from diabetes, we're toldthe cause is unknown. Well maybe that's not exactly true. Last month,the journal Neurology,an incredible study was published describing a relationship between what are called fluoroquinolones,and the risk of developing a peripheral neuropathy. You may not know what fluoroquinolones are,but chances are you may have actually been exposed to fluoroquinolone. These are antibioticsused for treating things like upper respiratory

infections and even urinary tract infections.Things like Levaquin and Cipro are commonly usedwalks. If you have a urinarytract infection, you may have received these mediations. Well, here's what the study showedus: So this is a study publishedSeptember2014 that looked at men between age 45 to 80 years of age followed for a 10 year periodandthis group there were over 6,000 cases of peripheral neuropathy. And they comparedthese individuals to about 25,000 aged match controls, and what they found was that riskfor developing this devastating condition called peripheral neuropathy was doubled inthose individuals exposed to this class of

antibiotics called fluoroquinolones. And whatthe researchers also told us is that, and I quote, quot;Fluoroquinolones have been shownto neurotoxic. Oral fluoroquinolones have also been associated with reported cases ofpsychosis and seizures, which similar to peripheral neuropathy have been shown to be acute eventsoccurring within days of fluoroquinolone use. In light of strong evidence of unnecessaryprescribing of oral fluoroquinolonesthe United States, ians must weigh the riskof PN against the benefits of prescribing FQ when prescribing these ugs to their patients.quot; We've got to practice medicine under the dictumof quot;above all do no harm.quot; One of our most

well respected peer journals is nowtelling us that the use of these mediions—these fluoroquinolone antibiotics is associatedwith doubling of the risk of peripheral neuropathy. A disease which often is not treatable. Sokeep thatmind the next time you think you need an antibiotic for this or that problem,discuss this study with your treating physician. I'm David Perlmutter.

Category: Diabetic Neuropathy

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